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Gensous N, Sala C, Pirazzini C, et al
By leveraging the favorable material properties of PNP hydrogels, this work aims to provide a next-generation injectable therapeutic platform to transform T2D management and improve adherence across chronic treatment landscapes
Mar 13 2020;12(3)doi:10.3390/nu12030757
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The initial twice-daily formulation was discontinued due to exceptionally high rates of gastrointestinal adverse events (nausea and vomiting), leading to discontinuation rates exceeding 50% in trials
The standard advice is "drink more water." This helps marginally, but the primary mechanism is slowed peristalsis, not dehydration
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