The nation is facing an obesity crisis
In a phase 2 trial, RETA achieved weight reductions of up to 24% after 48 weeks, approaching outcomes typically associated with bariatric surgery
GLP-1s may additionally impact other physiological changes observed in the perimenopausal period, including vasomotor symptoms like hot flashes and night sweats, declines in bone health, and unhealthy changes in body composition (gains in fat mass and declines in muscle mass), but whether these impacts are beneficial or harmful for women's health remains unknown
A major advantage is that they can be given orally while a potential disadvantage is that other hormones could also be affected
Pharmacology, Physiology, and Mechanisms of Incretin Hormone Action
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