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Some telehealth companies still offer compounded GLP-1s by using alternative language like GLP-1/GIP protocols or customized formulations. However, these are not FDA-approved and selling them without a documented clinical justification may be considered illegal

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Currently, retatrutide is in phase 3 clinical trials to determine its long-term safety and efficacy for weight loss in obese and overweight individuals, knee osteoarthritis, and obstructive sleep apnea

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Additionally, semaglutide slows gastric emptying, which prolongs the sensation of fullness after meals and reduces appetite through effects on appetite centers in the brain

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