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The observation that the insulinotropic actions of GLP-1 are reduced in type 2 diabetes mellitus (T2DM) led to the development of incretin-based therapies GLP-1 receptor agonists and dipeptidyl peptidase 4 (DPP-4) inhibitors for the treatment of hyperglycaemia in these patients
However, its short action duration necessitates frequent injections [97]
Neurochem Res 16: 10991111
In addition to its musculoskeletal benefits, BPC-157 helps protect and repair the gut lining, making it useful for those with gastrointestinal issues such as ulcers, leaky gut, or Crohns disease
JAMA Dermatology
However, the mechanism by which GLP-1R regulates the expression of p300 needs to be further investigated
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