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What it does suggest is that the 3- to 7-mg step may be a window of raised psychiatric risk in susceptible peopleplausibly through GLP-1 effects on mesolimbic dopamineand that a quick, validated mood check folded into the titration schedule would be a sensible precaution
*The anti-obesity drugs' estimated percentile ranking of weight loss of 10% in participants who took weight-loss medications for more than a year is Phentermine-Topiramate, 54%
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