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Undeniably, Ca 2+ fluxes are crucial for almost all reported RCD pathways in erythrocytes, whereas in apoptosis, Ca 2+ elevation mediates primarily the mitochondrial outer membrane permeabilization (MOMP), triggering the intrinsic apoptosis [192]
After lysis and release of the solubilized protein, the GST tagged protein is purified by affinity chromatography by adding 0.5ml glutathione resin to the clarified lysate
2.5 Core role of mitochondrial dysfunction in ferroptosis In recent years, a growing body of research has revealed that mitochondria play a key regulatory role in the occurrence and development of ferroptosis (114, 115)
A 2021 Nature Aging study by Lee and colleagues examined MOTS-c in the context of aging directly
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Flow cytometry was further applied to observe the cellular uptake of nanoparticles
