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NRP1 binds to S1 through a multi-basic furin-cleavage site (FCS) and promotes S1 shedding to expose the S2 site for TMPRSS2 priming 64

Study Limitations and Future Research Directions The interpretation of the findings is limited by the small GLP-1RA cohort (n = 12), baseline imbalances in BMI and sex, the single-center retrospective design, incomplete autoantibody testing, and a median follow-up of approximately eight months

Pancreatic safety of incretin-based drugsFDA and EMA assessment