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This narrative review aims to bridge the gap between evidence and clinical practice regarding the use of GLP-1 RAs in the perioperative period by critically evaluating changing clinical recommendations to inform a balance between the risks of aspiration and the potential surgical benefits

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These results also suggest that charge dependent adsorptive mediated transcytosis, which is prominent for cationic molecules and carriers, may not play a strong role in the internalization of drug-coupled 3-PLGs

GLP-1s have been shown to reduce inflammatory markers, such as C-reactive protein (CRP), and decrease the production of pro-inflammatory cytokines