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Both experimental and review articles addressing peptides efficacy and potential in systemic and ocular disease were included

A comprehensive review of the role of the microbiota-gut-brain axis via neuroinflammation: advances and therapeutic implications for ischemic stroke

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FDA banned it in late 2023 "Category 2: Substance with Safety Concerns" Why the FDA banned it: Potential immune reactions (immunogenicity) Manufacturing impurities in compounded versions Complete lack of human safety data Risk of contamination Legal status: NOT FDA-approved Illegal to compound in pharmacies Banned by WADA for athletes Possession not illegal (it's not a DEA scheduled substance) Sold online as "research chemical" 2

Nat Cancer 3(5):614628 Hackam DG, Hegele RA (2019) Cholesterol lowering and prevention of stroke

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