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At 0.5 mg per week, most people report minimal to no GI symptoms

Diabetes Obes Metab 2020

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This introduces an additional source of potential dosing error

Knowing that your 20-unit injection contains 1.6 mg helps you understand how your dose compares to published clinical trial data, where most patients achieved significant weight loss at doses ranging from 1.0 to 2.4 mg per week

In one study, people with opioid or alcohol use disorder who were taking GLP-1 medications had a 40 per cent lower rate of opioid overdose and a 50 per cent lower rate of alcohol intoxication compared to those not on the drugs