Beckman JS, Carson M, Smith CD, Kuppenol WH
Thus, melatonin appears to be a good candidate for neuroprotection because of its safety profile and different protective effects, including ROS scavenging, excitotoxic cascade blockade, and modulation of neuroinflammatory pathways 140
Expert Opin Drug Metab Toxicol 17:153169 Rosenkranz G (2020) Exploratory subgroup analyses in clinical research: Wiley 2020 Manson LE, van den Hout WB, Guchelaar H-J (2021) Genotyping for HLA risk alleles to prevent drug hypersensitivity reactions: impact analysis
While these findings remain encouraging, much of the published evidence has been generated through laboratory and animal models, and additional research is needed to further define its biological effects
10.3390/antiox9100948 246 SheppardD
Liang CM, Lee N, Cattell D, Liang SM