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It is speculated that the immune-regulatory effects of exenatide on the promotion of Tregs may be weak in pancreas of T2DM

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The shift toward chronic disease prevention and improved metabolic health is positioning GLP-1 receptor agonists as a cornerstone of modern obesity treatment strategies Restraint/Challenge Side Effects and High Treatment Costs Pose Adoption Barrier Concerns surrounding the side effects and high cost of GLP-1 receptor agonist therapies pose significant challenges to broader market adoption

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Studies show that GLP-1 drugs help reduce weight by improving satiety and decreasing cravings