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Zepbound: According to available clinical trials, it produces an average weight loss of 15-21% of body weight, making it one of the most effective prescription weight-loss medicines currently available

Unlike GLP-1 and dual agonists, metformin does not target appetite or hormone receptors but works mainly by enhancing how the body uses insulin

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Adams TD, Davidson LE, Litwin SE, Kim J, Kolotkin RL, Nanjee MN, et al

While semaglutide reduces your appetite, TRT helps build muscle and gives you the energy to make healthier food and exercise choices, says Kohn

Consult your healthcare provider before adding any supplement if you're on prescription medication