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Topcu A et al

Because the immune system plays an important role in controlling HSV-1 reactivation from the brain, episodes of immune-depression such as concomitant infections or stimuli, such as fever episodes may reactivate HSV-1 from neurons and allow the virus to enter a lytic replication cycle (Sawtell and Thompson, 2016)

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Skipping dose steps dramatically increases the risk and severity of adverse events

[DOI] [PubMed] Yu YC, Mao YM, Chen CW, Chen JJ, Chen J, Cong WM, et al
Furthermore, cysteamine has been recognized as an efficient depigmenting agent for melasma treatment (Besouw et al., 2013)

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