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The LR3 extension does not make it "safer" -- it makes it longer-acting and less regulated by binding proteins, which from a risk standpoint means sustained free IGF-1R activation without the IGFBP buffering system that modulates native IGF-1 activity in healthy physiology

It's significantly more resistant to degradation in acidic environments

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Doses dont need to be adjusted for age, though older skin may show effects more readily on some endpoints

Glutathione is often referred to as the master antioxidant for a reason

Facial flushing: A warm, flushed feeling in the face