Ozempic and Wegovy are the brand names for a drug called semaglutide
Contamination at any point introduces bacteria that multiply rapidly in the aqueous solution, causing infections at the injection site or systemic inflammatory responses
[57] Semaglutide blunts this LPS-induced release of pro-inflammatory cytokines
Other reported effects include: Abdominal discomfort or cramping Bloating and increased flatulence Dyspepsia (indigestion) Acid reflux or heartburn Less common but important side effects include gallbladder problems (such as gallstones) and, rarely, intestinal obstruction
Erin Palinksi-Wade, a registered dietician and board certified advisory member of Replenza, a new physician-formulated supplement system for GLP-1 users, says: There is a big interest in supplements that support the nutritional needs of GLP-1 users, partly because it is really hard for them to get everything they need nutritionally when theyre eating such a small amount of calories, but also to offset the side effects they can experience. As many as 68% of GLP-1 users stop taking the medications within one year, and Dr Alexandra Sowa, who specialises in internal and obesity medicine and has worked with GLP-1 patients for over a decade, says that the side effects can be difficult to navigate
Duman and Voleti, 2012