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Glucagon-like peptide-1 receptor agonists (GLP-1RAs) were initially developed for the treatment of type 2 diabetes mellitus and now have a key role in obesity management

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While the clinical trials for drugs like semaglutide (Wegovy/Ozempic) and tirzepatide (Zepbound/Mounjaro) demonstrate that efficacy is dose-dependent (higher doses yield more significant results), they also confirm that the initial, lower doses of the medications still provide measurable benefits for appetite suppression and blood sugar control

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