Survodutide (BI 456906) is a GLP-1R/GCGR dual agonist developed by Boehringer Ingelheim, with outcomes of a phase 2 trial in MASLD and a phase 1 trial in cirrhosis published almost simultaneously with tirzepatide
Victoza (liraglutide) is a GLP-1 receptor agonist licensed in the UK for treating type 2 diabetes mellitus
Data availability General synthesis procedure of LA-BPA derivatives as well as the NMR analysis characterizing LA-BPA derivatives are summarized in Supplementary Note 2 of Supplementary information file
The electrospun, waterless patch is made from upcycled feather-derived keratin and an active extracted from Sicilian pistachio hulls, a food industry byproduct that cofounder and chief executive officer Antonella Bellina described as a bunch of treasure. Activated by a light mist of water or applied to damp skin, the nanofiber patch dissolves on contact, delivering ingredients that help stimulate collagen while creating an invisible shield against pollution
Ginsenoside rg1 alleviates anit-induced cholestatic liver injury by inhibiting hepatic inflammation and oxidative stress via sirt1 activation
Anti-inflammatory mechanism through NF-B pathway modulation and cytokine response modulation provides a relatively well-defined research framework