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3 In REDEFINE 1, CagriSema produced 22.7% weight loss compared with 16.1% for semaglutide alone (the drug in Wegovy) over 68 weeks

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This study demonstrates superior outcomes of fusion over decompression alone for degenerative spondylolisthesis, establishing the current standard of care for this condition

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The combination supports liver-fat use without producing the full glucose response of glucagon alone, and the signal persists between doses

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