In addition to this, many people have problems metabolizing B12 in low-quality forms like cyanocobalamin due to defects in the MTHFR gene (1) (as many as 40% of people have THIS problem!)
Monitoring Treatment Response in Pernicious Anemia Its very important to keep an eye on patients with pernicious anemia to make sure vitamin B12 therapy is working
Supports proper hormone production, balance, and mood May reduce high blood levels of homocysteine (a substance thought to contribute to heart disease when elevated)
Adding too much water dilutes the solution, potentially requiring larger injection volumes that increase discomfort
Some vitamins are very difficult to get through diet and supplements are not always readily absorbed by the body
But for most purposes (like weekly maintenance injections), IM is the preferred route at home because its simpler (the vitamins absorb quickly from muscle into the bloodstream over a few hours)