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Selection of gene and metabolite lists In order to more precisely identify processes in gene set enrichment analyses by using bioinformatic tools we aimed to identify genes and metabolites associated with processes which would be relevant to action of GLP1RA and SGLT2i in the context of CV health

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However, if this severe elevation is accompanied by symptoms such as chest pain, severe headache, shortness of breath, neurological symptoms, or confusion, patients should call 911 immediately as this represents a hypertensive emergency requiring urgent treatment

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