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It modulates neutrophil and macrophage activity to dampen tissue-damaging inflammation and promotes clearance of infection

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Another important aspect of their research is that, for this system to function, the correct activity and coordinated action of the various enzymes involved in its complete breakdown are required, highlighting the complexity of these pathways and the ability of tumour cells to adapt and activate alternative metabolic routes

Proc Natl Acad Sci 89:444448 Kolesnik B, Palten K, Schrammel A, Stessel H, Schmidt K, Mayer B, Gorren AC (2013) Efficient nitrosation of glutathione by nitric oxide

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