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10.1016/j.nbd.2013.04.005 Neurobiol

Tesofensine (originally designated NS-2330) is a triple monoamine reuptake inhibitor that blocks the reuptake of three key neurotransmitters: Serotonin regulates mood and satiety signaling Norepinephrine increases metabolic rate and thermogenesis Dopamine modulates reward pathways and food cravings This triple mechanism is what makes tesofensine unique among weight loss compounds

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Do SGLT2 and GLP-1 therapies have a role in Lupus

Further studies are needed to investigate this hypothesis, but we suspect recent changes in medication prescribing practices and medication prices will result in large datasets allowing scientists to investigate these potential relationships. Christine Rode Schwarz, PhD, of the Steno Diabetes Center in Copenhagen, and her co-authors pointed to this case in a commentary titled, Mechanism and Context: Making Sense of Adverse Events With GLP-1-based Therapy , also published in JCEM Case Reports later that year