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These opposite findings regarding the GSHGABA+ relationship in the IFC and IPL suggest that the GSH function may differ according to the region, age and cognitive state of the individual
however, metformin is associated with failure in glycaemic control in approximately half of adolescents 13 , and insulin is associated with hypoglycaemia and weight gain 4,5
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Furthermore, research has identified unique gene expression profiles in the frontal cortex of individuals with depression, which are closely linked to emotion regulation and cognitive function [375]
doi: 10.1016/S0015-0282(02)04948-8 124 LuJWangZCaoJChenYDongY
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