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Make sure to see your provider regularly to monitor any drastic changes in your behavior or the appearance of thoughts of suicide

Weeks 12: 2 mg once weekly Weeks 36: 4 mg once weekly Weeks 710: 8 mg once weekly Week 11+: 12 mg once weekly (if tolerated) Fast escalation: Select cases, monitored closely This fast-escalation schedule is used only in specific situations where close supervision is available, such as in specialty clinics or structured clinical trial settings that follow strict safety protocols

ICER has also estimated current net annual prices in the thousands of dollars for these medications, underscoring why long-term affordability is such a central issue

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preprint: Desrochers et al , 2018)