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Figure 3 below summarizes these processes, highlighting the interplay between bacterial infection, immune mediators (e.g., TNF-, IL-6, transforming growth factor-beta [TGF-], IL-10), and cellular actors (e.g., neutrophils, M1/M2 macrophages, fibroblasts, keratinocytes, endothelial cells) during wound healing [43, 48]
Glutathione helps immune cells function optimally and aids with production of cytokines, which regulate the immune response and are necessary for an effective defensive against the Lyme bacteria.[ii] Glutathione can be administered orally or intravenously
10.1136/gutjnl-2014-307030 34 NieY.ErionD
10 Compared with non-tumor cells, tumor cells usually maintain high levels of NADPH, not only to power redox defense but also to use for biosynthetic reactions to sustain their rapid growth
J.BrackenboroughK.BriggsM
doi: 10.1038/s41581-018-0071-x 11 NobleJJouveTMalvezziPSsalCRostaingL
