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The phylogenetic tree was constructed by ClustalX version 1.81 and MEGA version 5, with a p -distance distribution, pairwise deletion, and bootstrap analysis of 10,000 repeats

1:1 propensity score matching was performed for demographics, comorbid conditions, body mass index (BMI) and body weight

GHK-Cu then provides the raw materials and genetic signals for optimal extracellular matrix production during the remodeling phase

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Additionally, reduced food intake often leads to lower fiber intake, which can affect gut health and worsen symptoms like constipation

Individuals using Mounjaro (Tirzepatide) may experience side effects such as constipation, which some have managed with probiotics