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Lipase activation leads to the release of fatty acids, which exacerbate pancreatic cell injury and accelerate inflammatory responses and cell death through multiple pathways ( 3.2 Dysregulation of glucose metabolism Dysregulation of glucose metabolism is another critical component of the metabolic disturbances observed in AP

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Chance TC, Herzig MC, Christy BA, Delavan C, Rathbone CR, Cap AP, et al

By altering these signals, the medication may decrease the reinforcing attributes of cocaine