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HR averaged over 24 h increased by 2 bpm with exenatide BID compared with a decrease of 1 bpm for placebo (n = 26) at the end of the study period [21]
Most patients begin noticing weight loss within the first few weeks of treatment
*Based on self-reported member data on a Found program from members with no prior weight loss medication use, who reported weight loss of 12.1% in 6 months on compounded tirzepatide, as of April 2026
Research from the STEP trials demonstrated that gastrointestinal effects occur in a large percentage of participants, though severity varies widely
The cold chain should be maintained from the time of compounding through dispensing and patient storage to ensure optimal medication quality
People with liver impairment or on certain antidepressants require prescriber review first
