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baseline) (STEP 1 trial extension)
Once the sequence was known and recombinant expression became routine, native-sequence human IGF-1 became available as a laboratory reagent and, separately, as a licensed protein under the name mecasermin
However, some studies on stem cell recovery in keratinocytes showed that copper-free GHK retained meaningful activity, suggesting the peptide backbone itself carries intrinsic biological information
Diabetes Med 2010;27:136-142
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