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Dysregulation of apoptotic pathways is a common feature in TNBC, often leading to chemoresistance and enabling tumor cells to evade cell death induced by conventional chemotherapeutic agents [92]
315,316,317 GLP-1R is expressed in human monocyte-derived macrophages and the mouse macrophage cell line RAW264.7
It is required for the proliferation and differentiation of lymphocytes, the production and activity of natural killer (NK) cells, and the regulation of cytokine signalling
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