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Thus, even plans sponsors who have so far elected not to cover GLP-1s for anti-obesity may still need to formulate a strategy to cover them as doctors begin to prescribe a greater variety of GLP-1s for a greater variety of conditions
16,27 A cohort study of 106 adults with obesity treated with semaglutide 2.4 mg showed an improvement in body composition, with a greater reduction in fat mass than lean mass, a reduction in the proportion of people with sarcopaenic obesity and a significant improvement in hand grip strength
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Kidney function effects follow comparable patterns
On the other hand, IGF-IR may trigger EMT via STAT3, FAK, and NF-kB [67, 68]
