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10.2337/db17-1385 3 AkimotoH.NegishiA.OshimaS.WakiyamaH.OkitaM.HoriiN.et al (2020)

rRNA, ribosomal RNA

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Indeed, seven doctors who spoke with Fortune say the preponderance of medical trials so far show that generally, people who stop taking the drugs regain most of the weight theyve lost within about a year

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Moreover, dysbiosis alters microbial metabolites, including short-chain fatty acids (SCFAs), trimethylamine N-oxide (TMAO), and indoles, which disrupts endocrine signaling (PYY, GLP-1/2, adiponectin, and resistin), impairs insulin pathways, and promotes lipogenesis, ultimately driving obesity and diabetes (Moszak et al., 2020)