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Most people take various oral supplements to maintain that balance, but that produces limited results

Individuals taking prescription medications, particularly those affecting blood sugar or blood pressure, should consult healthcare providers before combining treatments

Heat exposure: Do not leave the vial at room temperature longer than necessary for handling

Subsequent biochemical work demonstrated that only two enzyme systems require forms of vitamin B12 in man: adenosylcobalamin in the conversion of methylmalonyl coenzyme A to succinyl coenzyme A by methylmalonyl-coenzyme A mutase, and methylcobalamin in the conversion of homocysteine to methionine by methionine synthase (139)