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When paired with nutrition guidance, exercise recommendations, and ongoing support, GLP-1 medications help patients lose a significant percentage of body weight and maintain those results
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The metabolic impacts of GLP-1RAs go beyond their conventional functions, as they operate through a variety of interconnected systems linking the gastrointestinal (GI) tract, central nervous system (CNS), and immune system [5-7]
Yes, it is strongly recommended to follow cycles (e.g., 12 weeks on followed by 4 weeks off) to avoid receptor desensitization and to allow the endocrine system to function normally
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