10.1016/j.redox.2017.10.015 238
Diabetic wound healing studies using collagen dressings with GHK demonstrated 9-fold increase in collagen synthesis in healthy rats with higher glutathione and ascorbic acid levels, better epithelialization, and activation of fibroblasts and mast cells
Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue glutathione levels
GHK-Cus mechanism depends on gradual tissue accumulation over the cycle, not on high single-day concentrations
Often referred to as one of the body's primary endogenous antioxidants, Glutathione plays an important role in cellular defense mechanisms, oxidative balance, and metabolic processes
Methyl- and acetyl-groups determine how successful this is: methyl-groups close the DNA, whilst acetyl-groups open it