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If you have a lot of T4 and little T3, we know that something is blocking T4 from converting to T3 and that something is likely high reverse T3

Targeting oxidative stress in disease: promise and limitations of antioxidant therapy

This protective action is critical for maintaining oocyte quality and fertilization competence, as free radicals can cause significant damage to genetic material, impairing fertilization and early embryonic development []

It also reinforces the need for individualized assessment rather than a one-size-fits-all approach

The samples were centrifuged at 1.500 g for 10 min and the supernatant was stored at 80C for subsequent analyses