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doi: 10.1186/s12933-018-0800-2 198 MeierJJGethmannAGtzeOGallwitzBHolstJJSchmidtWEet al
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High blood sugar : When there is too much sugar in the bloodstream
The role of Ca 2+ ions in the function of NOS is related to the calmodulin subunits of NOS enzymes (see below)
(31) showed that neurons in the brains of patients with T2DM secrete the regulatory factor angiopoietin-like protein 8 (ANGPTL8) into the hippocampus, which activates microglia to up-regulate pro-inflammatory factors and axonal damage, leading to cognitive impairment
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