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Psychiatrists have full prescriptive authority for FDA-approved obesity medications and can use clinical judgment for off-label use (though some states like Mississippi prohibit off-label GLP-1s for weight loss)

Adjusting or dividing doses without professional medical supervision from a licensed pharmacist or physician carries significant risks

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Significant weight loss has traditionally been quantified as total body weight loss of 5 percent or more orforglipron exceeded that in this trial, says Dr

Corydon MJ, Vockley J, Rinaldo P, Rhead WJ, Kjeldsen M, Winter V et al