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Glutathione IV therapy inhibits melanin production, the pigment responsible for dark spots and discoloration, leading to a more uniform complexion
TRPV1 activation inhibits the dimerization of PKM2 and reduces the activation of SREBP1, thereby suppressing lipogenesis in microglia and potentially other tissues (97, 122)
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We hope this review can inspire the design and fabrication of PIPN-tailored drug and nanosystems for prevention and individualized treatment to raise the clinical benefits in patients treated with Pt-based chemotherapy
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