Observed in pilot human work A 2025 IV infusion pilot of BPC-157 in two adults at 10 mg and 20 mg reported no adverse effects on cardiac, hepatic, renal, thyroid, or glucose biomarkers (Lee et al., Alternative Therapies in Health and Medicine, 2025)
Glucose activates enteroendocrine hormone secretion via the sodiumglucose cotransporter 1 (SGLT1) [51]
Berberine, an alkaloid from various plants, activates metabolic regulatory enzymes and has been investigated for blood glucose control
FDA.gov / Regulations.gov (2024) 10
E.ElliottJ
Unfortunately, most interest in GLP-1 has focused on patentable drug treatments rather than nutritional interventions, so we dont know much about how our GLP-1 production responds to various nutrients in our food