For those reasons, the upper tolerable limit for daily Se consumption to prevent chronic toxicity was set to 300450 g by various guidelines, including the IOM, SCF, WHO/FAO, and the UK Expert Group on Vitamins and Minerals (51)
Because B12 injections are often categorized as self-pay wellness services, insurance typically only covers the cost if you have a documented medical diagnosis, like pernicious anemia or a severe clinical deficiency
alkanethiols or thiolated-polymer)
A clinical study involving 564 adults (BMI 30-40 kg/m2, without T2DM) found that compared with orlistat (3120 mg, weight loss of 4.1 kg), LIR (subcutaneous administration of 1.2 mg/d, 1.8 mg/d, 2.4 mg/d or 3 mg/d) had an average weight loss of 4.8-7.2 kg, the two-year extended experiment of which also showed similar results (88, 89)
however when you use these products, they can also enter your body through your skin
Milligan et al., 2022)