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BPC-157 modulates the VEGFR2 pathway to promote angiogenesis, activates the FAK-paxillin system to enhance cell migration toward injury sites, and influences nitric oxide production for improved blood flow
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From Rat Studies to Human Extrapolation From rat studies, the remarkably consistent effective dose range of 0.0045 mg/lb to 0.0000045 mg/lb intraperitoneally (a 1000-fold range showing similar efficacy) worked across depression, anxiety, Parkinsons, stroke, schizophrenia, and seizure models
the methyl group at the 1-position and the amino group at the 5-position appear important for inhibitory activity