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While these observational findings do not prove causation, they have prompted multiple prospective clinical trials investigating semaglutide specifically for neurodegenerative conditions

macros: 26g protein ~250 kcal Cost: ~$4.50 6

these factors make GLP-1 RAs an alternative initial treatment option, with or without metformin based on glycemic needs, in T2DM patients with indicators of high-risk or established heart failure (HF) or CKD who cannot tolerate an SGLT2 inhibitor

It neutralizes free radicals and toxins, subsequently attenuating oxidative damage and inflammatory responses (37, 38)

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