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Problem: Increased Fine Lines or Wrinkles Temporary increase in fine lines during weeks two through six can reflect normal collagen remodeling

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Cagrilintide is the most evidence-anchored option because CagriSema shows that adding amylin to a GLP-1 backbone improves outcomes

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doi:10.1042/bj0860173

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If you miss multiple days, there is no need to catch up with higher doses

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