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This potentially creates a vicious cycle leading to damage by free radicals unless the glutamatergic transmission is associated with increase in glutathione

The patient reported starting semaglutide for his diabetes approximately 1 month prior to presentation

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5 Mechanistically, exercise-induced interleukin-6 (IL-6) appears to stimulate GLP-1 secretion from intestinal L-cells and pancreatic -cells in experimental models, which may contribute to improved appetite regulation and insulin secretion during and after exercise