Results of in vitro experiments Cell growth curve assay HCT116 maintained good condition until 96 h of growth, with a growth bottleneck at 96 h and then entered a decline phase
Pearce, B.C., Parker, R.A., Deason, M.E., Qureshi, A.A., Wright, J.J., 1992
Lu SC: Regulation of glutathione synthesis
N-Acetylcysteine (NAC) - NAC is a direct precursor to cysteine , an essential amino acid needed for glutathione synthesis
Bilirubin is excreted in bile and urine, and elevated levels may indicate certain diseases
Additionally, individual susceptibility to ototoxicity varies, with preexisting conditions, such as chronic kidney disease and advanced age, further increasing vulnerability