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It was isolated and characterized by Professor Predrag Sikiric and colleagues at the University of Zagreb, who identified a partial sequence homology with a protein in human gastric juice

Bui TT, Piao CH, Hyeon E, Fan Y, Van Nguyen T, Jung SY, et al

Elevated copper can contribute to relative zinc deficiency, and chronic high-copper states can produce zinc depletion over time

Sun Y, Andrikopoulos N, Zhang G et al (2025) Formation of a -endorphin corona mitigates Alzheimers amyloidogenesis

WADA.org

Furthermore, the analysis revealed that two proteins present in exosomes were more abundant in patients at an active stage of inflammation as compared with controls