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Preclinical studies have demonstrated its efficacy in reducing myocardial infarct size in murine models of myocardial infarction and enhancing synaptic mitochondrial function in AD mouse models

Antigen Details Structure Monomer Distribution Astrocytes, hepatocytes, microglia, intestinal smooth muscle, myoblast, NK cells Function IGF-I induces mitogenesis, proliferation, growth, differentiation, and angiogenesis

Plevnik Kapun A, Salobir J, Levart A, Tavar Kalcher G, Nemec Svete A, Kotnik T

The authors established FOXO4-DRI as a first-in-class senolytic peptide tool for cellular senescence research, with mechanistic selectivity grounded in the elevated FOXO4-p53 interaction in senescent versus non-senescent cells

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Applied in the support of detoxing in cases of phenol toxicity too