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The relative fluorescence units (RFU) from each sample were normalized based on (1) hybridization controls on each microarray to correct for systematic variability in hybridization and (2) median signal based on all features for each dilution to correct for variability across plates according to the SomaScan Data Standardization guidelines (SomaScan Data Standardization and File Specification Technical Note (SSM-020))

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The typical price range charged to insurers for either is around $900-$1,300 per month, and one insurance plan will bring that cost down more or less than another, even within the same company

The convenience and cost savings of staying on continuous therapy usually outweigh the appeal of breaks

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Sources: Fras, Juan P., et al